If two genes for sickling are inherited, you have full blown sickle cell anemia, and you produce mainly Hb S. Symptoms of sickle cell anemia the usual symptoms of anemia, plus jaundice usually appear at about six months of age, shortly after the production of hemoglobin F stops. Clots caused by sickled red cells blocking the circulation of blood may form in the hands and feet, causing severe pain and swelling. The spleen may malfunction and swell up filling the abdominal cavity a life threatening emergency. At times your body may be incapable of fighting in factions.
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